The Journal of Immunology ImmunoCastsAuthor: AAI
19 Dec 2018

The Journal of Immunology ImmunoCasts

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The Journal of Immunology ImmunoCasts

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    [IMMUNOCAST] PILLARS OF IMMUNOLOGY

    Dr. Dr. Mark Kaplan discusses a 1989 Science paper by Gerald Crabtree that demonstrated the mechanism by which cyclosporin A inhibited T cell activation.

  • Posted on 19 Nov 2018

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    [IMMUNOCAST] PILLARS OF IMMUNOLOGY

    Dr. Uttiya Basu discusses a 1999 paper by the group of Tasuku Honjo that demonstrates a critical role for activation-induced cytidine deaminase in class switch recombination and somatic hypermutation of B cells.

  • Posted on 22 Oct 2018

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    [IMMUNOCAST] PILLARS OF IMMUNOLOGY

    Dr. Luc van Kaer discusses a 1994 paper by the group of Dr. Don Wiley that demonstrated the binding of superantigens with the MHC class II molecule.

  • Posted on 17 Sep 2018

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    [IMMUNOCAST] PILLARS OF IMMUNOLOGY

    Dr. Martin Flajnik discusses a 2004 Nature paper by Drs. Max Cooper and Zeev Pancer that identified the existence of variable lymphocyte receptors that which were generated by non-RAG-based rearrangement events.

  • Posted on 20 Aug 2018

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    [IMMUNOCAST] PILLARS OF IMMUNOLOGY

    Dr. Wolf H. Fridman discusses a 2001 paper by the group of Robert Schreiber that established the foundations of modern immune-oncology.

  • Posted on 23 Jul 2018

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